The death of the dog can finally occur, if the dog is not provided an effective and adapted veterinary care. A dog female which spayed before the occurrence of the first heat has almost a possibility zero of the development of the cancer mammaire, which is more common with the dogs which not spayed.
A dog female generally comes to heat once in eight month or thus. During the occurrence of heat, there bleeds of the vagina and the dog can cross with the non desired male and the spaying activity prevents all the latter. In the event of old dogs, the dog can often obtain signs of thirst, anorexia increased, vomiting etc which are so common with the pyometry.